Watch Jen interact with the adorable Hayli and her mom in this year’s PSA for St. Jude’s Thanks & Giving campaign here.

Jennifer has also written a post for The Huffington Post with Marlo Thomas to bring awareness to St. Jude’s Children Research Hospital. You can read their post here.

“Hi, Marlo and Jennifer here-posting together!

For a few years, we had a great time playing mother and daughter on Friends. Not only did we share tons of laughs together (and who couldn’t laugh on the set of Friends?), but we also discovered that our most famous TV characters had a shared legacy as women. In a way, Friends’ Rachel Green was not all that different from That Girl’s Ann Marie — they were both independent, strong-minded and funny. So I guess you could say that, in the annals of TV history, we’re cross-generational soul-sisters!

[...]

Since 2006, Jen has donated her time and talent by filming spots for St. Jude Children’s Research Hospital, sharing the screen with one or more of our adorable St. Jude kids. You’ve probably seen the spots on TV (or in movie theaters, or even on airplanes). One mother did, and it changed her life. She had a very sick little girl named McKenna, whose symptoms — chronic headaches — persisted, even after several consultations with the family doctor. Then the mom saw one of Jen’s St. Jude spots, featuring a child with brain cancer, who had suffered the same symptoms. Empowered by what she saw, she rushed her daughter to St. Jude for treatment. That little girl is alive today.

McKenna’s mom wrote Jennifer a touching letter, thanking her for guiding her to St. Jude — and for Jen, the experience was profoundly moving. Can you imagine anything more rewarding than knowing that you somehow helped save a child’s life?”

It’s that time of the year again. St. Jude’s Children’s Research Hospital and Jennifer, alongside Robin Williams, Morgan Freeman, George Lopez, Shaun White, Dwyane Wade, singer Luis Fonsi and St. Jude National Outreach Director Marlo Thomas, are teaming up with the patients of St. Jude to tell us about their mission of saving these adorable children.

Check out the trailer and look forward to a special TV spot with Jennifer and Hayli, which is supposed to debut on November 22.

Jennifer is nominated at the 2012′s People’s Choice Awards in the categories Favorite Comedic Movie Actress and Favorite Movie Actress. You can vote for her here (Comedic Actress) and here (Movie Actress).

Two of Jennifer’s close friends are also nominated. Courteney Cox for Favorite TV Comedy Actress and Ellen DeGeneres for Favorite Day Time Host.

Tonight, the 2011′s Glamour Women of the Year awards will be held at Carnegie Hall in New York City. Jennifer will present Chelsea Handler with The Queen of the Night award. We don’t have any details other than that for now. But you can follow Glamour on Twitter for some live-tweeting.

Here we go, people! Check it out! And count the days until February 24, 2012…